IDS

Across TCGA patient cohorts, IDS protein abundance is significantly associated with the RNA expression of many other genes, with 7,702 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IDS-associated genes across cancer lineages are BCO2, CD86, and SNX20. Each is linked with IDS in more than 4 cancer types. Because this analysis shows association rather than direction, both IDS-to-partner and partner-to-IDS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IDS versus BCO2 in HNSC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IDS→partner) and Y-score (partner→IDS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BCO2 →	+0.540	+0.303	.006	.007	3	5
UCEC	CD86 →	+0.791	+0.351	.003	.008	3	4
UCEC	SNX20 →	+0.698	+0.364	.002	.007	3	4
LSCC	GK3P →	+0.429	+0.443	.001	.001	3	4
UCEC	LCP2 →	+0.861	+0.438	.001	<.001	3	4
CCRCC	PCED1B-AS1 →	+0.463	+0.224	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,702 associations by consensus.

IDS vs BCO2 — HNSC

Explore this scatter interactively →