IDNK

Across TCGA patient cohorts, IDNK protein abundance is significantly associated with the RNA expression of many other genes, with 13,652 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IDNK-associated genes across cancer lineages are KIF14, PFDN4, and TTK. Each is linked with IDNK in more than 5 cancer types. Because this analysis shows association rather than direction, both IDNK-to-partner and partner-to-IDNK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IDNK versus KIF14 in GBM, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IDNK→partner) and Y-score (partner→IDNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KIF14 →	-1.008	-0.440	<.001	<.001	3	6
LSCC	PFDN4 →	-0.542	-0.239	<.001	.002	3	5
BRCA	TTK →	-1.069	-0.401	<.001	<.001	3	5
GBM	NCAPH →	-0.941	-0.509	<.001	<.001	3	5
LUAD	CCNB1 →	-0.902	-0.258	<.001	<.001	3	5
BRCA	CENPO →	-0.565	-0.523	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,652 associations by consensus.

IDNK vs KIF14 — GBM

Explore this scatter interactively →