IDNK

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IDNK RNA expression is significantly associated with the go_rna of many other GO terms, with 2,471 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IDNK-associated GO terms across cancer lineages are Negative regulation of macrophage chemotaxis, Fatty acid beta-oxidation, and Fatty acid catabolic process. Each is linked with IDNK in more than 10 cancer types. Because this analysis shows association rather than direction, both IDNK-to-partner and partner-to-IDNK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of macrophage chemotaxis grouped by IDNK-low versus IDNK-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IDNK→partner) and Y-score (partner→IDNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINNegative regulation of macrophage chemotaxis →-0.164-1.040<.001<.001311
LARGE_INTESTINEFatty acid beta-oxidation →+0.082+1.074<.001<.001310
STOMACHFatty acid catabolic process →+0.071+1.121.003.00938
UPPER_AERODIGESTIVE_TRACTPhosphatidylethanolamine acyl-chain remodeling →+0.110+1.069<.001<.00138
LARGE_INTESTINEFatty acid oxidation →+0.059+0.772<.001<.00138
STOMACHL-leucine metabolic process →+0.198+1.528<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,471 associations by consensus.

Negative regulation of macrophage chemotaxis by IDNK expression — SKIN

Box plot of Negative regulation of macrophage chemotaxis in IDNK-low vs IDNK-high samples in SKIN.

Explore this box plot interactively →

Exploration