IDNK

Across TCGA cell cohorts, IDNK mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IDNK-associated genes across cancer lineages are OR51T1, GSG1L2, and LCE1F. Each is linked with IDNK in more than 1 cancer types. Because this analysis shows association rather than direction, both IDNK-to-partner and partner-to-IDNK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51T1 grouped by IDNK-low versus IDNK-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IDNK→partner) and Y-score (partner→IDNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
LARGE_INTESTINE	LCE1F →	+0.122	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR51T1 by IDNK expression — BLOOD_Leukemia

Explore this box plot interactively →