IDI2

Across TCGA patient cohorts, IDI2 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IDI2-associated genes across cancer lineages are RNA5SP329, RNU6-905P, and OR5AP2. Each is linked with IDI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IDI2-to-partner and partner-to-IDI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP329 grouped by IDI2-low versus IDI2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IDI2→partner) and Y-score (partner→IDI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP329 →	+0.349	+5.106	<.001	.008	3	2
SKCM	RNU6-905P →	+0.366	+5.513	<.001	.004	3	2
SKCM	OR5AP2 →	+0.311	+5.097	.002	.008	3	2
SKCM	IQCF5-AS1 →	+0.024	+5.362	<.001	.005	3	1
SKCM	ANKRD26P2 →	+0.054	+5.362	<.001	.005	3	1
BLCA	PDE2A-AS1 →	+0.088	+4.973	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

RNA5SP329 by IDI2 expression — BLCA

Explore this box plot interactively →