IDI1

Across TCGA pan-cancer cohorts, IDI1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated IDI1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher IDI1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated IDI1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

PDAC, UCEC, and LUAD are the cancer types where IDI1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	II,III,IV	0.458	0.235	.004	24	view →
UCEC	OS	Median	III,IV	1.000	0.433	.007	12	view →
LUAD	DFS	Tertile	All	0.486	0.792	.006	8	view →
HNSC	DFS	Tertile	III,IV	0.782	0.496	.016	5	view →
LSCC	OS	Quartile	III,IV	0.603	0.918	.045	4	view →
CCRCC	DFS	Median	All	0.544	0.891	.027	3	view →
GBM	OS	Quartile	All	0.937	0.607	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

IDI1–PDAC (OS)

Open the PDAC breakdown →