IDI1

Across TCGA pan-cancer cohorts, IDI1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of IDI1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where IDI1 RNA is repressed in tumor relative to normal tissue. In most cancer types IDI1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and THCA are the cancer types where IDI1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IDI1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	−0.958	<.001	11	view →
KICH	Male	All	−1.205	<.001	10	view →
THCA	Male	III,IV	−0.969	<.001	10	view →
KIRP	Male	All	−1.339	<.001	9	view →
LUAD	Female	II,III,IV	−1.328	<.001	9	view →
LIHC	All	III,IV	+1.356	<.001	8	view →
LUSC	All	All	−0.513	<.001	7	view →
BRCA	All	All	+0.299	.010	6	view →
COAD	Female	IV	−0.854	.028	1	view →
STAD	All	All	+0.340	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

IDI1–KIRC

Open the KIRC breakdown →