IDI1

Across TCGA patient cohorts, IDI1 mutation is significantly associated with the RNA expression of many other genes, with 1,675 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IDI1-associated genes across cancer lineages are LONRF2P1, PRAMEF13, and MIR7854. Each is linked with IDI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IDI1-to-partner and partner-to-IDI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LONRF2P1 grouped by IDI1-low versus IDI1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IDI1→partner) and Y-score (partner→IDI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LONRF2P1 →	+0.096	+5.812	<.001	.003	3	2
UCEC	PRAMEF13 →	+0.020	+2.951	<.001	.007	3	2
BRCA	MIR7854 →	+0.575	+4.098	.003	.004	3	1
BRCA	MIR6853 →	+0.145	+7.057	<.001	.009	3	1
UCEC	CCDC163 →	+0.528	+2.545	<.001	.001	3	1
UCEC	LINC01943 →	+0.444	+3.202	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,675 associations by consensus.

LONRF2P1 by IDI1 expression — CESC

Explore this box plot interactively →