IDI1

Across TCGA cell cohorts, IDI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,199 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IDI1-associated GO terms across cancer lineages are Cholesterol biosynthetic process via lathosterol, Zymosterol metabolic process, and Zymosterol biosynthetic process. Each is linked with IDI1 in more than 19 cancer types. Because this analysis shows association rather than direction, both IDI1-to-partner and partner-to-IDI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cholesterol biosynthetic process via lathosterol grouped by IDI1-low versus IDI1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IDI1→partner) and Y-score (partner→IDI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cholesterol biosynthetic process via lathosterol →	+0.201	+1.009	<.001	<.001	3	20
BREAST	Zymosterol metabolic process →	+0.210	+1.495	<.001	<.001	3	20
BREAST	Zymosterol biosynthetic process →	+0.210	+1.495	<.001	<.001	3	20
PANCREAS	Farnesyl diphosphate biosynthetic process, mevalonate pathway →	+0.218	+1.366	<.001	<.001	3	19
OVARY	Sterol biosynthetic process →	+0.175	+1.175	<.001	<.001	3	19
OVARY	Secondary alcohol biosynthetic process →	+0.188	+1.125	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,199 associations by consensus.

Cholesterol biosynthetic process via lathosterol by IDI1 expression — OESOPHAGUS

Explore this box plot interactively →