IDH3G

Across TCGA patient cohorts, IDH3G protein abundance is significantly associated with the RNA expression of many other genes, with 15,934 significant associations in total. COAD shows the largest number of these associations.

The most reproducible IDH3G-associated genes across cancer lineages are SERPINH1, MRPL3, and FAM81A. Each is linked with IDH3G in more than 4 cancer types. Because this analysis shows association rather than direction, both IDH3G-to-partner and partner-to-IDH3G results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IDH3G versus SERPINH1 in GBM, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IDH3G→partner) and Y-score (partner→IDH3G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SERPINH1 →	-0.812	-0.294	.001	.002	3	5
BRCA	MRPL3 →	-0.470	-0.272	<.001	<.001	3	4
UCEC	FAM81A →	+1.012	+0.292	.001	<.001	3	4
OV	COX5A →	+0.505	+0.304	<.001	<.001	3	4
BRCA	BRIX1 →	-0.481	-0.278	<.001	<.001	3	4
HNSC	SNRPF →	-0.671	-0.184	.004	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,934 associations by consensus.

IDH3G vs SERPINH1 — GBM

Explore this scatter interactively →