IDH3G

Across TCGA cell cohorts, IDH3G RNA expression is significantly associated with the go_rna of many other GO terms, with 3,582 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IDH3G-associated GO terms across cancer lineages are Positive regulation of microtubule nucleation, Tricarboxylic acid metabolic process, and Positive regulation of anaphase-promoting complex-dependent catabolic process. Each is linked with IDH3G in more than 11 cancer types. Because this analysis shows association rather than direction, both IDH3G-to-partner and partner-to-IDH3G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of microtubule nucleation grouped by IDH3G-low versus IDH3G-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IDH3G→partner) and Y-score (partner→IDH3G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of microtubule nucleation →	+0.125	+0.432	<.001	<.001	3	11
LARGE_INTESTINE	Tricarboxylic acid metabolic process →	+0.114	+0.887	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.107	+0.601	<.001	<.001	2	12
SOFT_TISSUE	GDP-mannose biosynthetic process →	+0.109	+0.488	<.001	<.001	3	10
SOFT_TISSUE	Negative regulation of NLRP3 inflammasome complex assembly →	+0.137	+0.642	<.001	<.001	3	10
LARGE_INTESTINE	Response to iron(III) ion →	+0.170	+0.733	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,582 associations by consensus.

Positive regulation of microtubule nucleation by IDH3G expression — SKIN

Explore this box plot interactively →