IDH3B

Across TCGA patient cohorts, IDH3B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,218 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IDH3B-associated proteins across cancer lineages are TRMT6, PCNA, and TRMT61A. Each is linked with IDH3B in more than 7 cancer types. Because this analysis shows association rather than direction, both IDH3B-to-partner and partner-to-IDH3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IDH3B versus TRMT6 in LSCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IDH3B→partner) and Y-score (partner→IDH3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRMT6 →	+0.434	+0.538	<.001	<.001	3	8
LSCC	PCNA →	+0.468	+0.451	<.001	<.001	3	8
PDAC	TRMT61A →	+0.402	+0.250	<.001	<.001	3	7
LSCC	FASTKD5 →	+0.478	+0.478	<.001	<.001	3	7
LSCC	CRNKL1 →	+0.336	+0.516	<.001	<.001	3	7
GBM	XRN2 →	+0.227	+0.336	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,218 associations by consensus.

IDH3B vs TRMT6 — LSCC

Explore this scatter interactively →