IDE

Across TCGA patient cohorts, IDE protein abundance is significantly associated with the protein abundance of many other proteins, with 19,977 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IDE-associated proteins across cancer lineages are GLRX3, PPA1, and SEC24C. Each is linked with IDE in more than 8 cancer types. Because this analysis shows association rather than direction, both IDE-to-partner and partner-to-IDE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IDE versus GLRX3 in LSCC, with a Pearson correlation of 0.45.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IDE→partner) and Y-score (partner→IDE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GLRX3 →	+0.434	+0.324	<.001	<.001	3	9
COAD	PPA1 →	+0.912	+0.337	<.001	<.001	3	8
HNSC	SEC24C →	+0.265	+0.400	<.001	<.001	3	7
LUAD	MICU2 →	+0.491	+0.381	<.001	<.001	3	7
UCEC	BTAF1 →	+0.235	+0.280	<.001	<.001	3	7
OV	COPB1 →	+0.229	+0.244	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,977 associations by consensus.

IDE vs GLRX3 — LSCC

Explore this scatter interactively →