ID4

Across TCGA cell cohorts, ID4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,021 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ID4-associated GO terms across cancer lineages are Regulation of monoatomic cation transmembrane transport, Negative regulation of mRNA catabolic process, and Regulation of protein processing. Each is linked with ID4 in more than 8 cancer types. Because this analysis shows association rather than direction, both ID4-to-partner and partner-to-ID4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of monoatomic cation transmembrane transport grouped by ID4-low versus ID4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ID4→partner) and Y-score (partner→ID4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of monoatomic cation transmembrane transport →	-0.082	-2.884	<.001	<.001	3	9
BONE	Negative regulation of mRNA catabolic process →	+0.068	+2.135	<.001	<.001	3	9
SOFT_TISSUE	Regulation of protein processing →	-0.203	-3.003	<.001	<.001	3	8
STOMACH	Regulation of potassium ion transmembrane transport →	-0.167	-2.385	.002	.007	3	8
STOMACH	Regulation of termination of RNA polymerase II transcription →	+0.153	+2.933	<.001	<.001	3	8
LIVER	Positive regulation of double-strand break repair via homologous recombination →	+0.101	+3.654	.002	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,021 associations by consensus.

Regulation of monoatomic cation transmembrane transport by ID4 expression — OVARY

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