ID4

Across TCGA cell cohorts, ID4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ID4-associated genes across cancer lineages are NLRP8 and SUPT20HL1. Each is linked with ID4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ID4-to-partner and partner-to-ID4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NLRP8 grouped by ID4-low versus ID4-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ID4→partner) and Y-score (partner→ID4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	NLRP8 →	+0.006	+5.196	<.001	.005	3	1
OVARY	SUPT20HL1 →	+0.123	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

NLRP8 by ID4 expression — OVARY

Explore this box plot interactively →