ID2-AS1

Across TCGA pan-cancer cohorts, ID2-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ID2-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ID2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ID2-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and UCS show a favorable association.

ACC, LGG, and UCS are the cancer types where ID2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.380	0.761	<.001	94	view →
LGG	OS	Median	All	0.869	0.749	<.001	40	view →
UCS	DFS	Median	All	0.394	0.173	.009	38	view →
BLCA	OS	Median	II,III,IV	0.662	0.549	.005	31	view →
LUAD	DFS	Median	IV	0.306	0.764	.010	29	view →
COAD	DFS	Tertile	All	0.702	0.440	.013	13	view →
KICH	OS	Median	All	0.691	1.000	.004	10	view →
CHOL	OS	Tertile	All	0.955	0.296	.002	9	view →
READ	DFS	Quartile	III,IV	1.000	0.455	.024	9	view →
SKCM	DFS	Quartile	All	0.667	0.527	.011	6	view →
MESO	DFS	Tertile	IV	0.127	0.505	.019	6	view →
LIHC	DFS	Quartile	II,III,IV	0.241	0.391	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ID2-AS1–ACC (DFS)

Open the ACC breakdown →