ID1

Across TCGA cell cohorts, ID1 mutation is significantly associated with the mutation status of many other genes, with 1,846 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ID1-associated genes across cancer lineages are C3orf20, RNASEL, and FBLN7. Each is linked with ID1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ID1-to-partner and partner-to-ID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C3orf20 grouped by ID1-low versus ID1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ID1→partner) and Y-score (partner→ID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	C3orf20 →	+5.415	+5.415	.004	.004	1	2
OVARY	RNASEL →	+4.415	+4.977	.007	.007	1	2
OVARY	FBLN7 →	+4.415	+4.977	.007	.007	1	2
OVARY	OSBPL11 →	+4.415	+4.977	.007	.007	1	2
OVARY	GTF3C5 →	+4.415	+4.977	.007	.007	1	2
OVARY	ZNF326 →	+5.415	+5.415	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,846 associations by consensus.

C3orf20 by ID1 expression — OVARY

Explore this box plot interactively →