ICE2P1

Across TCGA patient cohorts, ICE2P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,452 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ICE2P1-associated GO terms across cancer lineages are tRNA modification, Mitochondrial transport, and Regulation of signal transduction by p53 class mediator. Each is linked with ICE2P1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ICE2P1-to-partner and partner-to-ICE2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA modification grouped by ICE2P1-low versus ICE2P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ICE2P1→partner) and Y-score (partner→ICE2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	tRNA modification →	+0.051	+0.088	<.001	<.001	3	16
STAD	Mitochondrial transport →	+0.054	+0.085	<.001	<.001	3	16
ESCA	Regulation of signal transduction by p53 class mediator →	+0.083	+0.137	<.001	.004	3	15
STAD	Transcription by RNA polymerase III →	+0.057	+0.090	<.001	<.001	3	15
ESCA	RNA modification →	+0.053	+0.121	.001	.003	3	15
STAD	Mitochondrial gene expression →	+0.062	+0.103	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,452 associations by consensus.

tRNA modification by ICE2P1 expression — STAD

Explore this box plot interactively →