ICE1

Across TCGA patient cohorts, ICE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,971 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ICE1-associated proteins across cancer lineages are WDR70, NSUN2, and MSH2. Each is linked with ICE1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ICE1-to-partner and partner-to-ICE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ICE1 versus WDR70 in LSCC, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ICE1→partner) and Y-score (partner→ICE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR70 →	+0.348	+0.533	<.001	<.001	3	7
LUAD	NSUN2 →	+0.454	+0.595	<.001	<.001	3	6
GBM	MSH2 →	+0.435	+0.335	.005	<.001	3	6
LSCC	ICE1_S533 →	+0.814	+0.989	<.001	<.001	3	6
GBM	ZFR →	+0.262	+0.417	<.001	<.001	3	6
HNSC	NUP155 →	+0.175	+0.725	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,971 associations by consensus.

ICE1 vs WDR70 — LSCC

Explore this scatter interactively →