ICAM5

Across TCGA patient cohorts, ICAM5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,485 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ICAM5-associated proteins across cancer lineages are ICAM1, IL4I1, and SPP1_S195. Each is linked with ICAM5 in more than 6 cancer types. Because this analysis shows association rather than direction, both ICAM5-to-partner and partner-to-ICAM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ICAM5 versus ICAM1 in LUAD, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ICAM5→partner) and Y-score (partner→ICAM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ICAM1 →	+0.692	+1.294	<.001	<.001	3	7
COAD	IL4I1 →	+0.812	+0.481	<.001	<.001	3	5
CCRCC	SPP1_S195 →	+1.024	+0.664	.001	<.001	3	4
CCRCC	SPP1_S234 →	+1.422	+0.608	<.001	<.001	3	4
CCRCC	SPP1_S275 →	+0.990	+0.546	<.001	.002	3	4
BRCA	PRR15 →	-0.804	-0.781	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,485 associations by consensus.

ICAM5 vs ICAM1 — LUAD

Explore this scatter interactively →