ICAM5

Across TCGA patient cohorts, ICAM5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,349 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ICAM5-associated genes across cancer lineages are MEIS3, ZFP37, and ZCCHC24. Each is linked with ICAM5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ICAM5-to-partner and partner-to-ICAM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ICAM5 versus MEIS3 in GBM, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ICAM5→partner) and Y-score (partner→ICAM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MEIS3 →	+0.833	+0.610	<.001	<.001	3	3
LUAD	ZFP37 →	+0.451	+0.411	<.001	<.001	3	3
LUAD	ZCCHC24 →	+0.504	+0.407	<.001	.002	3	3
GBM	TMEM130 →	+1.936	+0.957	<.001	<.001	3	3
GBM	GALNT17 →	+1.093	+0.593	<.001	<.001	3	3
PDAC	PLPPR2 →	+0.514	+0.926	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,349 associations by consensus.

ICAM5 vs MEIS3 — GBM

Explore this scatter interactively →