ICAM5

Across TCGA cell cohorts, ICAM5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,291 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ICAM5-associated GO terms across cancer lineages are Establishment of RNA localization, Nuclear export, and Nucleic acid catabolic process. Each is linked with ICAM5 in more than 11 cancer types. Because this analysis shows association rather than direction, both ICAM5-to-partner and partner-to-ICAM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of RNA localization grouped by ICAM5-low versus ICAM5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ICAM5→partner) and Y-score (partner→ICAM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Establishment of RNA localization →	+0.094	+1.564	.006	.001	2	12
BREAST	Nuclear export →	+0.082	+1.686	<.001	.001	3	10
OESOPHAGUS	Nucleic acid catabolic process →	+0.065	+2.199	.003	<.001	3	10
BONE	RNA catabolic process →	+0.061	+2.365	.002	<.001	3	10
STOMACH	RNA export from nucleus →	+0.118	+1.815	<.001	<.001	3	10
BREAST	RNA localization →	+0.104	+1.943	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,291 associations by consensus.

Establishment of RNA localization by ICAM5 expression — OESOPHAGUS

Explore this box plot interactively →