ICAM1

Across TCGA pan-cancer cohorts, ICAM1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ICAM1 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ICAM1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ICAM1 expression acts as an unfavorable survival marker.

COAD, PDAC, and CCRCC are the cancer types where ICAM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	II,III,IV	0.792	1.000	.008	114	view →
PDAC	OS	Median	III,IV	0.537	1.000	.008	14	view →
CCRCC	OS	Quartile	All	0.777	0.964	.003	8	view →
LSCC	OS	Quartile	II,III,IV	0.628	1.000	.013	4	view →
GBM	OS	Quartile	All	0.355	0.592	.017	3	view →
HNSC	OS	Quartile	II,III,IV	0.697	0.924	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ICAM1–COAD (DFS)

Open the COAD breakdown →