ICAM1

Across TCGA patient cohorts, ICAM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,918 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ICAM1-associated proteins across cancer lineages are SPN, TNFAIP8L2, and MNDA. Each is linked with ICAM1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ICAM1-to-partner and partner-to-ICAM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ICAM1 versus SPN in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ICAM1→partner) and Y-score (partner→ICAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SPN →	+0.630	+1.093	<.001	<.001	3	9
COAD	TNFAIP8L2 →	+0.628	+1.146	<.001	<.001	3	9
GBM	MNDA →	+0.892	+1.382	<.001	<.001	3	9
BRCA	THEMIS2_T593 →	+0.824	+1.416	<.001	<.001	3	8
GBM	MYO1F →	+0.620	+1.283	<.001	<.001	3	8
GBM	MYO1G →	+0.649	+1.339	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,918 associations by consensus.

ICAM1 vs SPN — OV

Explore this scatter interactively →