ICAM1

Across TCGA patient cohorts, ICAM1 protein abundance is significantly associated with the RNA expression of many other genes, with 24,391 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ICAM1-associated genes across cancer lineages are CD86, RAC2, and GPR84. Each is linked with ICAM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ICAM1-to-partner and partner-to-ICAM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ICAM1 versus CD86 in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ICAM1→partner) and Y-score (partner→ICAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CD86 →	+1.054	+0.557	<.001	<.001	3	10
OV	RAC2 →	+1.494	+0.612	<.001	.001	3	10
OV	GPR84 →	+1.207	+0.627	<.001	.001	3	10
OV	SLAMF8 →	+1.120	+0.586	<.001	<.001	3	10
OV	LAPTM5 →	+1.456	+0.639	<.001	<.001	3	10
OV	LAIR1 →	+1.164	+0.616	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,391 associations by consensus.

ICAM1 vs CD86 — OV

Explore this scatter interactively →