ICA1L

Across TCGA cell cohorts, ICA1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,648 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ICA1L-associated GO terms across cancer lineages are Transport along microtubule, Cytoskeleton-dependent intracellular transport, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ICA1L in more than 15 cancer types. Because this analysis shows association rather than direction, both ICA1L-to-partner and partner-to-ICA1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport along microtubule grouped by ICA1L-low versus ICA1L-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ICA1L→partner) and Y-score (partner→ICA1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Transport along microtubule →	+0.079	+1.443	<.001	<.001	3	16
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.085	+1.620	<.001	<.001	3	15
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.101	+1.045	<.001	.001	3	15
OESOPHAGUS	Golgi vesicle transport →	+0.091	+0.777	.001	.002	3	15
LUNG_SCLC	Mitotic cytokinesis →	+0.086	+1.063	<.001	.002	2	15
URINARY_TRACT	Cytoskeleton-dependent cytokinesis →	+0.076	+1.159	.002	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,648 associations by consensus.

Transport along microtubule by ICA1L expression — LUNG_SCLC

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