IBTK

Across TCGA patient cohorts, IBTK RNA expression is significantly associated with the protein abundance of many other proteins, with 10,671 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IBTK-associated proteins across cancer lineages are PGM3, IBTK_S1069, and PRRC1. Each is linked with IBTK in more than 5 cancer types. Because this analysis shows association rather than direction, both IBTK-to-partner and partner-to-IBTK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IBTK versus PGM3 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IBTK→partner) and Y-score (partner→IBTK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PGM3 →	+0.321	+0.420	<.001	<.001	3	6
BRCA	IBTK_S1069 →	+0.668	+0.804	.004	.002	3	5
OV	PRRC1 →	+0.364	+0.588	<.001	<.001	3	4
GBM	RNGTT →	+0.397	+0.419	<.001	<.001	3	4
OV	SLIRP →	-0.543	-0.665	<.001	<.001	3	4
COAD	LRPPRC →	-0.447	-0.601	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,671 associations by consensus.

IBTK vs PGM3 — GBM

Explore this scatter interactively →