IBSP

Across TCGA patient cohorts, IBSP RNA expression is significantly associated with the protein abundance of many other proteins, with 10,339 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IBSP-associated proteins across cancer lineages are FN1, SRPX2, and THBS2. Each is linked with IBSP in more than 5 cancer types. Because this analysis shows association rather than direction, both IBSP-to-partner and partner-to-IBSP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IBSP versus FN1 in COAD, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IBSP→partner) and Y-score (partner→IBSP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FN1 →	+0.661	+1.143	<.001	<.001	3	6
COAD	SRPX2 →	+0.792	+1.731	<.001	<.001	3	6
CCRCC	THBS2 →	+1.310	+1.080	<.001	<.001	3	6
CCRCC	BMP1 →	+1.160	+1.723	.003	<.001	3	6
CCRCC	AEBP1 →	+0.789	+0.832	.001	.002	3	6
CCRCC	EDIL3 →	+0.726	+1.073	.004	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,339 associations by consensus.

IBSP vs FN1 — COAD

Explore this scatter interactively →