IBSP

Across TCGA patient cohorts, IBSP protein abundance is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IBSP-associated genes across cancer lineages are UBBP3, KRTAP1-1, and LINC01728. Each is linked with IBSP in more than 1 cancer types. Because this analysis shows association rather than direction, both IBSP-to-partner and partner-to-IBSP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IBSP versus UBBP3 in GBM, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IBSP→partner) and Y-score (partner→IBSP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	UBBP3 →	+0.483	+1.911	<.001	.009	3	1
GBM	KRTAP1-1 →	+0.215	+2.268	.003	.004	1	1
GBM	LINC01728 →	+0.260	+2.268	.003	.004	1	1
GBM	RPL21P127 →	+0.280	+2.268	.002	.004	1	1
GBM	SUMO2P4 →	+0.455	+2.268	.002	.004	1	1
GBM	PHOX2B-AS1 →	+0.215	+2.325	.003	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

IBSP vs UBBP3 — GBM

Explore this scatter interactively →