IBA57

Across TCGA patient cohorts, IBA57 mutation is significantly associated with the RNA expression of many other genes, with 861 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IBA57-associated genes across cancer lineages are RNA5SP410, LINC00363, and SNORD126. Each is linked with IBA57 in more than 2 cancer types. Because this analysis shows association rather than direction, both IBA57-to-partner and partner-to-IBA57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP410 grouped by IBA57-low versus IBA57-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IBA57→partner) and Y-score (partner→IBA57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP410 →	+0.628	+2.052	<.001	.009	3	3
UCEC	LINC00363 →	+0.125	+2.912	.001	.009	3	2
COAD	SNORD126 →	+1.029	+4.861	<.001	<.001	3	2
STAD	RNA5SP93 →	+0.376	+3.830	<.001	.006	3	2
HNSC	MIR5591 →	+0.698	+7.954	<.001	.008	3	2
BRCA	RNA5SP423 →	+0.260	+7.731	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 861 associations by consensus.

RNA5SP410 by IBA57 expression — UCEC

Explore this box plot interactively →