IBA57

Across TCGA cell cohorts, IBA57 mutation is significantly associated with the mutation status of many other genes, with 3,515 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IBA57-associated genes across cancer lineages are SARM1, PITX1, and EPN2. Each is linked with IBA57 in more than 2 cancer types. Because this analysis shows association rather than direction, both IBA57-to-partner and partner-to-IBA57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SARM1 grouped by IBA57-low versus IBA57-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IBA57→partner) and Y-score (partner→IBA57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SARM1 →	+3.215	+3.415	.002	.002	1	3
LARGE_INTESTINE	PITX1 →	+3.630	+3.630	.001	.001	1	3
BLOOD_Leukemia	EPN2 →	+5.145	+5.145	<.001	<.001	1	3
BLOOD_Leukemia	BAG6 →	+2.823	+3.665	.008	.008	1	3
BLOOD_Leukemia	AP4M1 →	+3.338	+4.083	.003	.003	1	3
BLOOD_Leukemia	PCDHGA3 →	+2.975	+3.794	.006	.006	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,515 associations by consensus.

SARM1 by IBA57 expression — LARGE_INTESTINE

Explore this box plot interactively →