IARS2

Across TCGA patient cohorts, IARS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,528 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IARS2-associated proteins across cancer lineages are C1orf35, BROX, and CDC73. Each is linked with IARS2 in more than 8 cancer types. Because this analysis shows association rather than direction, both IARS2-to-partner and partner-to-IARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IARS2 versus C1orf35 in COAD, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IARS2→partner) and Y-score (partner→IARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C1orf35 →	+0.528	+0.478	<.001	<.001	3	9
LSCC	BROX →	+0.483	+0.714	<.001	<.001	3	8
UCEC	CDC73 →	+0.304	+0.942	<.001	.002	3	8
UCEC	PARP1 →	+0.417	+0.818	<.001	<.001	3	7
COAD	CTR9 →	+0.283	+0.546	<.001	<.001	3	7
LSCC	IPO9 →	+0.331	+0.563	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,528 associations by consensus.

IARS2 vs C1orf35 — COAD

Explore this scatter interactively →