IAH1

Across TCGA patient cohorts, IAH1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IAH1-associated genes across cancer lineages are ATP6V1E1P2, RNU6-336P, and RPL30P5. Each is linked with IAH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IAH1-to-partner and partner-to-IAH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP6V1E1P2 grouped by IAH1-low versus IAH1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IAH1→partner) and Y-score (partner→IAH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP6V1E1P2 →	+0.237	+3.661	.005	.009	3	1
UCEC	RNU6-336P →	+0.380	+4.267	.001	.009	3	1
UCEC	RPL30P5 →	+0.316	+4.764	<.001	.001	3	1
UCEC	RN7SL307P →	+0.301	+3.903	.007	.006	3	1
UCEC	IGKV2D-19 →	+0.242	+4.520	.003	.001	3	1
LUSC	RNU6-266P →	+0.438	+7.924	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ATP6V1E1P2 by IAH1 expression — UCEC

Explore this box plot interactively →