HYPK

Across TCGA patient cohorts, HYPK RNA expression is significantly associated with the protein abundance of many other proteins, with 10,965 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HYPK-associated proteins across cancer lineages are RPS27, MRPL50, and CNNM3. Each is linked with HYPK in more than 3 cancer types. Because this analysis shows association rather than direction, both HYPK-to-partner and partner-to-HYPK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HYPK versus RPS27 in HNSC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HYPK→partner) and Y-score (partner→HYPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPS27 →	-0.558	-0.533	<.001	<.001	3	4
UCEC	MRPL50 →	-0.303	-0.605	<.001	<.001	3	4
UCEC	CNNM3 →	+0.426	+0.631	<.001	<.001	3	4
CCRCC	TMEM237_S25 →	-0.501	-0.218	<.001	<.001	3	3
GBM	TRAF7_S108 →	-0.362	-0.308	.003	.001	3	3
BRCA	WASHC2A_S539 →	-1.121	-0.202	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,965 associations by consensus.

HYPK vs RPS27 — HNSC

Explore this scatter interactively →