HYPK

Across TCGA patient cohorts, HYPK protein abundance is significantly associated with the RNA expression of many other genes, with 13,043 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HYPK-associated genes across cancer lineages are RBMS3, CCT5, and LMOD1. Each is linked with HYPK in more than 6 cancer types. Because this analysis shows association rather than direction, both HYPK-to-partner and partner-to-HYPK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HYPK versus RBMS3 in HNSC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HYPK→partner) and Y-score (partner→HYPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RBMS3 →	-0.625	-0.316	.002	.001	3	7
UCEC	CCT5 →	+1.449	+0.320	<.001	<.001	3	5
BRCA	LMOD1 →	-1.006	-0.206	<.001	.001	3	5
UCEC	MAD2L1 →	+1.326	+0.300	<.001	<.001	3	5
LSCC	NAA15 →	+0.564	+0.171	<.001	<.001	3	5
LSCC	SNRPD1 →	+0.754	+0.149	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,043 associations by consensus.

HYPK vs RBMS3 — HNSC

Explore this scatter interactively →