HYPK

Across TCGA cell cohorts, HYPK RNA expression is significantly associated with the RNA expression of many other genes, with 8,888 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HYPK-associated genes across cancer lineages are NOP10, COX6A1, and COX7A2. Each is linked with HYPK in more than 14 cancer types. Because this analysis shows association rather than direction, both HYPK-to-partner and partner-to-HYPK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HYPK versus NOP10 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.67.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HYPK→partner) and Y-score (partner→HYPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	NOP10 →	+1.271	+2.201	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	COX6A1 →	+0.950	+1.520	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	COX7A2 →	+1.300	+1.482	<.001	<.001	3	13
URINARY_TRACT	MRPS18C →	+1.135	+1.505	.001	<.001	3	13
BONE	ATP5MD →	+1.072	+1.866	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	ATP5MC1 →	+1.709	+2.166	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,888 associations by consensus.

HYPK vs NOP10 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →