Across TCGA patient cohorts, HYLS1 mutation is significantly associated with the RNA expression of many other genes, with 1,419 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HYLS1-associated genes across cancer lineages are LINC01789, BNIP3P6, and RPS19P6. Each is linked with HYLS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HYLS1-to-partner and partner-to-HYLS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HYLS1→partner) and Y-score (partner→HYLS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC01789 →	+0.120	+4.800	.001	.006	3	2
UCEC	BNIP3P6 →	+0.029	+4.390	<.001	.003	3	2
SKCM	RPS19P6 →	+0.129	+5.097	<.001	.008	3	1
UCEC	DCP1A →	+0.512	+3.212	.005	.009	3	1
UCEC	CWC25 →	+0.434	+2.823	.002	.001	3	1
UCEC	ZNHIT3 →	+0.530	+3.108	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,419 associations by consensus.

Exploration

HYLS1 survival (RNA) · tumor vs normal (RNA) · all HYLS1 data types