HYDIN

Across TCGA patient cohorts, HYDIN RNA expression is significantly associated with the go_rna of many other GO terms, with 7,164 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HYDIN-associated GO terms across cancer lineages are Intraciliary anterograde transport, Microtubule-based transport, and Intraciliary transport involved in cilium assembly. Each is linked with HYDIN in more than 29 cancer types. Because this analysis shows association rather than direction, both HYDIN-to-partner and partner-to-HYDIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary anterograde transport grouped by HYDIN-low versus HYDIN-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HYDIN→partner) and Y-score (partner→HYDIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Intraciliary anterograde transport →	+0.096	+0.182	<.001	<.001	3	30
STAD	Microtubule-based transport →	+0.044	+0.130	<.001	<.001	3	28
UCS	Intraciliary transport involved in cilium assembly →	+0.077	+0.576	<.001	<.001	3	28
UCEC	Intraciliary transport →	+0.060	+0.847	<.001	<.001	3	28
ESCA	Non-motile cilium assembly →	+0.059	+0.143	<.001	<.001	3	27
STAD	Protein targeting to lysosome →	+0.075	+0.156	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,164 associations by consensus.

Intraciliary anterograde transport by HYDIN expression — ESCA

Explore this box plot interactively →