HYDIN

Across TCGA patient cohorts, HYDIN protein abundance is significantly associated with the RNA expression of many other genes, with 2,636 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HYDIN-associated genes across cancer lineages are ZFAND1, SCO1, and CFAP94. Each is linked with HYDIN in more than 1 cancer types. Because this analysis shows association rather than direction, both HYDIN-to-partner and partner-to-HYDIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HYDIN versus ZFAND1 in UCEC, with a Pearson correlation of -0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HYDIN→partner) and Y-score (partner→HYDIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZFAND1 →	-0.463	-1.278	.009	<.001	3	2
UCEC	SCO1 →	-0.890	-1.135	.004	.001	3	2
LUAD	CFAP94 →	+0.908	+0.721	<.001	.003	3	2
LSCC	BPIFB1 →	+2.753	+1.130	.005	.001	3	2
LUAD	C2orf50 →	+0.539	+0.672	.001	.004	3	2
LSCC	DNAAF1 →	+1.308	+1.316	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,636 associations by consensus.

HYDIN vs ZFAND1 — UCEC

Explore this scatter interactively →