HYDIN

Across TCGA cell cohorts, HYDIN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,824 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HYDIN-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with HYDIN in more than 13 cancer types. Because this analysis shows association rather than direction, both HYDIN-to-partner and partner-to-HYDIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by HYDIN-low versus HYDIN-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HYDIN→partner) and Y-score (partner→HYDIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.132	+0.867	<.001	<.001	3	14
OVARY	Negative regulation of myoblast fusion →	+0.110	+0.622	<.001	.002	3	14
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.129	+0.901	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.127	+0.368	<.001	.001	3	13
STOMACH	Nuclear export →	+0.083	+0.598	.002	.002	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.082	+0.315	<.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,824 associations by consensus.

Regulation of myoblast fusion by HYDIN expression — OVARY

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