HYAL1

Across TCGA patient cohorts, HYAL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,943 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HYAL1-associated proteins across cancer lineages are LAMB2, CALR, and PLOD1. Each is linked with HYAL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HYAL1-to-partner and partner-to-HYAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HYAL1 versus LAMB2 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HYAL1→partner) and Y-score (partner→HYAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LAMB2 →	+0.900	+0.699	<.001	<.001	3	5
GBM	CALR →	-0.253	-0.362	.002	<.001	3	4
CCRCC	PLOD1 →	-0.357	-0.706	<.001	<.001	3	4
CCRCC	PLOD2 →	-0.958	-0.867	<.001	.003	3	4
GBM	PLOD3 →	-0.510	-0.338	<.001	.001	3	4
UCEC	RRM1 →	-0.493	-0.543	.003	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,943 associations by consensus.

HYAL1 vs LAMB2 — BRCA

Explore this scatter interactively →