HYAL1

Across TCGA cell cohorts, HYAL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,313 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HYAL1-associated GO terms across cancer lineages are Cellular response to alcohol, Fatty acid catabolic process, and Fatty acid beta-oxidation. Each is linked with HYAL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HYAL1-to-partner and partner-to-HYAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to alcohol grouped by HYAL1-low versus HYAL1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HYAL1→partner) and Y-score (partner→HYAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Cellular response to alcohol →	+0.106	+3.458	.006	.003	3	7
STOMACH	Fatty acid catabolic process →	+0.102	+2.530	<.001	.002	2	8
OESOPHAGUS	Fatty acid beta-oxidation →	+0.091	+1.840	.004	<.001	2	8
LUNG_NSCLC_LUSC	Negative regulation of acute inflammatory response →	+0.313	+0.928	<.001	.005	3	6
STOMACH	Organic acid catabolic process →	+0.076	+2.743	.001	.003	3	6
STOMACH	Carboxylic acid catabolic process →	+0.076	+2.743	.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,313 associations by consensus.

Cellular response to alcohol by HYAL1 expression — LIVER

Explore this box plot interactively →