HTRA3

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HTRA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,776 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HTRA3-associated proteins across cancer lineages are CCDC80, COPZ2, and FKBP7. Each is linked with HTRA3 in more than 9 cancer types. Because this analysis shows association rather than direction, both HTRA3-to-partner and partner-to-HTRA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTRA3 versus CCDC80 in OV, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HTRA3→partner) and Y-score (partner→HTRA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCCDC80 →+1.083+1.331<.001<.001310
OVCOPZ2 →+1.042+1.403<.001<.001310
OVFKBP7 →+0.615+1.122<.001<.001310
GBMRCN3 →+0.860+0.778<.001<.00139
GBMASPN →+1.152+1.331<.001<.00139
OVSH3PXD2B →+0.492+1.622<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,776 associations by consensus.

HTRA3 vs CCDC80 — OV

Per-sample scatter of HTRA3 vs CCDC80 in OV (Pearson r = 0.65).

Explore this scatter interactively →

Exploration