HTR3E-AS1

Across TCGA pan-cancer cohorts, HTR3E-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of HTR3E-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where HTR3E-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types HTR3E-AS1 is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

COAD, THCA, and BLCA are the cancer types where HTR3E-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HTR3E-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.053	.002	4	view →
THCA	All	All	−0.028	.009	2	view →
BLCA	All	III,IV	+0.084	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

HTR3E-AS1–COAD

Open the COAD breakdown →