Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, HTR3D mutation is significantly associated with the RNA expression of many other genes, with 2,746 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible HTR3D-associated genes across cancer lineages are H2BC17, H2AC14, and PIGW. Each is linked with HTR3D in more than 1 cancer types. Because this analysis shows association rather than direction, both HTR3D-to-partner and partner-to-HTR3D results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (HTR3D→partner) and Y-score (partner→HTR3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.