HTR3A

Across TCGA patient cohorts, HTR3A RNA expression is significantly associated with the protein abundance of many other proteins, with 7,340 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HTR3A-associated proteins across cancer lineages are PSME3, RASAL1, and OSBPL3_S437. Each is linked with HTR3A in more than 3 cancer types. Because this analysis shows association rather than direction, both HTR3A-to-partner and partner-to-HTR3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR3A versus PSME3 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR3A→partner) and Y-score (partner→HTR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PSME3 →	+0.215	+1.315	.002	.006	3	3
UCEC	RASAL1 →	+0.461	+0.626	.003	<.001	3	3
UCEC	OSBPL3_S437 →	+0.542	+0.642	.006	.001	3	3
LUAD	PEAK1 →	-0.235	-1.303	.001	.004	3	3
CCRCC	RRBP1_S615 →	+0.864	+0.439	<.001	.001	3	3
BRCA	BAG1 →	-0.360	-0.262	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,340 associations by consensus.

HTR3A vs PSME3 — OV

Explore this scatter interactively →