HTR1F

Across TCGA patient cohorts, HTR1F mutation is significantly associated with the RNA expression of many other genes, with 4,308 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HTR1F-associated genes across cancer lineages are RN7SL663P, CYP2T1P, and RNU4-65P. Each is linked with HTR1F in more than 2 cancer types. Because this analysis shows association rather than direction, both HTR1F-to-partner and partner-to-HTR1F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL663P grouped by HTR1F-low versus HTR1F-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR1F→partner) and Y-score (partner→HTR1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL663P →	-0.259	-1.734	.005	.002	3	3
COAD	CYP2T1P →	-0.686	-3.571	<.001	.002	3	3
UCEC	RNU4-65P →	+0.089	+2.324	<.001	.007	3	3
CESC	FAM90A27P →	+0.704	+3.934	<.001	.005	3	2
UCEC	NFYBP1 →	+0.167	+1.510	<.001	.001	3	2
SKCM	MIR6076 →	+0.212	+2.145	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,308 associations by consensus.

RN7SL663P by HTR1F expression — UCEC

Explore this box plot interactively →