HTR1B

Across TCGA cell cohorts, HTR1B RNA expression is significantly associated with the go_rna of many other GO terms, with 446 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HTR1B-associated GO terms across cancer lineages are Regulation of negative chemotaxis, SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition, and ATP biosynthetic process. Each is linked with HTR1B in more than 3 cancer types. Because this analysis shows association rather than direction, both HTR1B-to-partner and partner-to-HTR1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of negative chemotaxis grouped by HTR1B-low versus HTR1B-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR1B→partner) and Y-score (partner→HTR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of negative chemotaxis →	+0.721	+0.137	.001	.008	3	4
BLOOD_Leukemia	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.053	+0.156	.002	.004	3	4
BLOOD_Leukemia	ATP biosynthetic process →	+0.046	+0.102	.003	.006	3	4
BLOOD_Leukemia	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.037	-0.108	<.001	.004	3	4
STOMACH	Regulation of serotonin secretion →	+0.994	+1.233	<.001	.004	3	4
BLOOD_Leukemia	Regulation of skeletal muscle adaptation →	-0.251	-0.117	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 446 associations by consensus.

Regulation of negative chemotaxis by HTR1B expression — BLOOD_Leukemia

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