HTR1A

Across TCGA patient cohorts, HTR1A RNA expression is significantly associated with the RNA expression of many other genes, with 7,685 significant associations in total. LGG shows the largest number of these associations.

The most reproducible HTR1A-associated genes across cancer lineages are ANKRD34C-AS1, SLC7A14, and TMEM151B. Each is linked with HTR1A in more than 11 cancer types. Because this analysis shows association rather than direction, both HTR1A-to-partner and partner-to-HTR1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR1A versus ANKRD34C-AS1 in COAD, with a Pearson correlation of 0.94.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR1A→partner) and Y-score (partner→HTR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ANKRD34C-AS1 →	+0.620	+0.332	<.001	<.001	3	12
LGG	SLC7A14 →	+1.542	+1.377	<.001	<.001	3	12
LGG	TMEM151B →	+1.894	+1.526	<.001	<.001	3	12
LGG	SLC17A6 →	+1.252	+1.317	<.001	<.001	3	11
LGG	PAK3 →	+1.424	+1.534	<.001	<.001	3	10
PCPG	TMEM196 →	+1.311	+0.768	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,685 associations by consensus.

HTR1A vs ANKRD34C-AS1 — COAD

Explore this scatter interactively →