HTD2

Across TCGA patient cohorts, HTD2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,135 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HTD2-associated genes across cancer lineages are CSF2RB, CXCR1, and ZNF57. Each is linked with HTD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both HTD2-to-partner and partner-to-HTD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTD2 versus CSF2RB in COAD, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTD2→partner) and Y-score (partner→HTD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CSF2RB →	-0.932	-0.619	.002	.007	3	2
COAD	CXCR1 →	-1.620	-0.931	.008	.003	3	2
LSCC	ZNF57 →	+0.271	+0.319	<.001	<.001	3	2
COAD	CXCR2 →	-1.279	-0.908	.002	.002	3	2
LSCC	PELATON →	-0.690	-0.485	<.001	<.001	3	2
COAD	MIR223HG →	-0.996	-0.680	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,135 associations by consensus.

HTD2 vs CSF2RB — COAD

Explore this scatter interactively →